Eating disorders and autism: extension of the PEACE pathway to children and young people
References
- American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-5). Arlington, VA. American Psychiatric Association (2013). https://doi.org/10.1007/springerreference_179660
- Zeidan J, Fombonne E, Scorah J, Ibrahim A, Durkin MS, Saxena S, et al. Global prevalence of autism: a systematic review update. Autism Research. 2022;15(5):778-90. https://doi.org/10.1002/aur.2696
- Center for Disease Control (CDC) Autism and Developmental Disabilities Monitoring (ADDM) Network. Data and statistics on autism spectrum disorder 2024. Accessed 24 June 2024. Available from: https://www.cdc.gov/autism/data-research/index.html. https://doi.org/10.1007/s10803-018-3500-6
- Loomes R, Hull L, Mandy WPL. What is the male-to-female ratio in autism spectrum disorder? A systematic review and meta-analysis. Journal of the American Academy of Child and Adolescent Psychiatry. 2017;56(6):466-74. https://doi.org/10.1016/j.jaac.2017.03.013
- Gillberg C. Are autism and anorexia nervosa related? The British Journal of Psychiatry. 1983;142:428.
- Gillberg CL. The Emanuel Miller Memorial Lecture 1991. Journal of Child Psychology and Psychiatry. 1992;33(5):813-42.
- Solmi F, Bentivegna F, Bould H, Mandy W, Kothari R, Rai D, et al. Trajectories of autistic social traits in childhood and adolescence and disordered eating behaviours at age 14 years: a UK general population cohort study. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 2021;62(1):75-85. https://doi.org/10.1111/jcpp.13255
- Lang K, Lopez C, Stahl D, Tchanturia K, Treasure J. Central coherence in eating disorders: an updated systematic review and meta-analysis. The World Journal of Biological Psychiatry. 2014;15(8):586-98. https://doi.org/10.3109/15622975.2014.909606
- Lopez C, Tchanturia K, Stahl D, Treasure J. Weak central coherence in eating disorders: a step towards looking for an endophenotype of eating disorders. Journal of Clinical and Experimental Neuropsychology. 2009;31(1):117-25. https://doi.org/10.1080/13803390802036092
- Holliday J, Tchanturia K, Landau S, Collier D, Treasure J. Is impaired set-shifting an endophenotype of anorexia nervosa? American Journal of Psychiatry. 2005;162(12):2269-75. https://doi.org/10.1176/appi.ajp.162.12.2269
- Lilenfeld LR, Kaye WH, Greeno CG, Merikangas KR, Plotnicov K, Pollice C, et al. A controlled family study of anorexia nervosa and bulimia nervosa: psychiatric disorders in first-degree relatives and effects of proband comorbidity. Archives of General Psychiatry. 1998;55(7):603- 10. https://doi.org/10.1001/archpsyc.55.7.603
- Anderluh MB, Tchanturia K, Rabe-Hesketh S, Treasure J. Childhood obsessive-compulsive personality traits in adult women with eating disorders: defining a broader eating disorder phenotype. American Journal of Psychiatry. 2003;160(2):242-7. https://doi.org/10.1176/appi.ajp.160.2.242
- Westwood H, Eisler I, Mandy W, Leppanen J, Treasure J, Tchanturia K. Using the autism-spectrum quotient to measure autistic traits in anorexia nervosa: a systematic review and meta-analysis. Journal of Autism and Developmental Disorders. 2016;46(3):964-77. https://doi.org/10.1007/s10803-015-2641-0
- Rhind C, Bonfioli E, Hibbs R, Goddard E, Macdonald P, Gowers S, et al. An examination of autism spectrum traits in adolescents with anorexia nervosa and their parents. Molecular Autism. 2014;5(1):56. https://doi.org/10.1186/2040-2392-5-56
- Oldershaw A, Hambrook D, Stahl D, Tchanturia K, Treasure J, Schmidt U. The socio-emotional processing stream in anorexia nervosa. Neuroscience and Biobehavioral Reviews. 2011;35(3):970-88. https://doi.org/10.1016/j.neubiorev.2010.11.001
- Leppanen J, Sedgewick F, Treasure J, Tchanturia K. Differences in the theory of mind profiles of patients with anorexia nervosa and individuals on the autism spectrum: a meta-analytic review. Neuroscience and Biobehavioral Reviews. 2018;90:146-63. https://doi.org/10.1016/j.neubiorev.2018.04.009
- Oldershaw A, Treasure J, Hambrook D, Tchanturia K, Schmidt U. Is anorexia nervosa a version of autism spectrum disorders? European Eating Disorders Review. 2011;19(6):462-74. https://doi.org/10.1002/erv.1069
- Zucker NL, Losh M, Bulik CM, LaBar KS, Piven J, Pelphrey KA. Anorexia nervosa and autism spectrum disorders: guided investigation of social cognitive endophenotypes. Psychological Bulletin. 2007;133(6):976-1006. https://doi.org/10.1037/0033-2909.133.6.976
- Schröder SS, Danner UN, Spek AA, van Elburg AA. Exploring the intersection of autism spectrum disorder and eating disorders: understanding the unique challenges and treatment considerations for autistic women with eating disorders. Current Opinion in Psychiatry. 2023;36(6):419-26. https://doi.org/10.1097/yco.0000000000000894
- Tchanturia K, Adamson J, Leppanen J, Westwood H. Characteristics of autism spectrum disorder in anorexia nervosa: a naturalistic study in an inpatient treatment programme. Autism. 2019;23(1):123-30. https://doi.org/10.1177/1362361317722431
- Saure E, Laasonen M, Lepistö-Paisley T, Mikkola K, Ålgars M, Raevuori A. Characteristics of autism spectrum disorders are associated with longer duration of anorexia nervosa: a systematic review and meta-analysis. The International Journal of Eating Disorders. 2020;53(7):1056- 79. https://doi.org/10.1002/eat.23259
- Saure E, Laasonen M, Raevuori A. Anorexia nervosa and comorbid autism spectrum disorders. Current Opinion in Psychiatry. 2021;34(6):569-75. https://doi.org/10.1097/yco.0000000000000742
- Nuyttens M, Simons A, Antrop I, Glazemakers I. A longitudinal study of autism spectrum disorder characteristics in adolescents with restrictive type anorexia nervosa during and after underweight. European Eating Disorders Review. 2024;32(2):310-21. https://doi.org/10.1002/erv.3042
- Westwood H, Tchanturia K. Autism spectrum disorder in anorexia nervosa: an updated literature review. Current Psychiatry Reports. 2017;19(7):41. https://doi.org/10.1007/s11920-017-0791-9
- Boltri M, Sapuppo W. Anorexia nervosa and autism spectrum disorder: a systematic review. Psychiatry Research. 2021;306:114271. https://doi.org/10.1016/j.psychres.2021.114271
- Dinkler L, Taylor MJ, Röstam M, Hadjikhani N, Bulik CM, Lichtenstein P, et al. Anorexia nervosa and autism: a prospective twin cohort study. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 2021;62(3):316-26. https://doi.org/10.1111/jcpp.13265
- Hiller R, Pellicano L. Anorexia and autism: a cautionary note. Psychologist. 2013;26(11):780.
- Treasure J, Willmott D, Ambwani S, Cardi V, Clark Bryan D, Rowlands K, et al. Cognitive interpersonal model for anorexia nervosa revisited: the perpetuating factors that contribute to the development of the severe and enduring illness. Journal of Clinical Medicine. 2020;9(3):630. https://doi.org/10.3390/jcm9030630
- Tchanturia K, Morris RG, Anderluh MB, Collier DA, Nikolaou V, Treasure J. Set shifting in anorexia nervosa: an examination before and after weight gain, in full recovery and relationship to childhood and adult OCPD traits. Journal of Psychiatric Research. 2004;38(5):545-52. https://doi.org/10.1016/j.jpsychires.2004.03.001
- Danner UN, Sanders N, Smeets PAM, van Meer F, Adan RAH, Hoek HW, et al. Neuropsychological weaknesses in anorexia nervosa: setshifting, central coherence, and decision making in currently ill and recovered women. International Journal of Eating Disorders. 2012;45(5):685-94. https://doi.org/10.1002/eat.22007
- Lindner SE, Fichter MM, Quadflieg N. Set-shifting and its relation to clinical and personality variables in full recovery of anorexia nervosa. European Eating Disorders Review. 2014;22(4):252-9. https://doi.org/10.1002/erv.2293
- Nazar BP, Peynenburg V, Rhind C, Hibbs R, Schmidt U, Gowers S, et al. An examination of the clinical outcomes of adolescents and young adults with broad autism spectrum traits and autism spectrum disorder and anorexia nervosa: a multi centre study. The International Journal of Eating Disorders. 2018;51(2):174-9. https://doi.org/10.1002/eat.22823
- Råstam M, T.ljemark J, Tajnia A, Lundström S, Gustafsson P, Lichtenstein P, et al. Eating problems and overlap with ADHD and autism spectrum disorders in a nationwide twin study of 9- and 12-year-old children. The Scientific World Journal. 2013;2013(1):315429. https://doi.org/10.1155/2013/315429
- Koch SV, Larsen JT, Mouridsen SE, Bentz M, Petersen L, Bulik C, et al. Autism spectrum disorder in individuals with anorexia nervosa and in their first- and second-degree relatives: Danish nationwide register-based cohort-study. The British Journal of Psychiatry. 2015;206(5):401-7. https://doi.org/10.1192/bjp.bp.114.153221
- Baron-Cohen S, Jaffa T, Davies S, Auyeung B, Allison C, Wheelwright S. Do girls with anorexia nervosa have elevated autistic traits? Molecular Autism. 2013;4(1):24. https://doi.org/10.1186/2040-2392-4-24
- Tchanturia K, Smith E, Weineck F, Fidanboylu E, Kern N, Treasure J, et al. Exploring autistic traits in anorexia: a clinical study. Molecular Autism. 2013;4(1):44. https://doi.org/10.1186/2040-2392-4-44
- Westwood H, Mandy W, Tchanturia K. Clinical evaluation of autistic symptoms in women with anorexia nervosa. Molecular Autism. 2017;8:12. https://doi.org/10.1186/s13229-017-0128-x
- Westwood H, Mandy W, Simic M, Tchanturia K. Assessing ASD in Adolescent females with anorexia nervosa using clinical and developmental measures: a preliminary investigation. Journal of Abnormal Child Psychology. 2018;46(1):183-92. https://doi.org/10.1007/s10802-017-0301-x
- Kerr-Gaffney J, Hayward H, Jones EJH, Halls D, Murphy D, Tchanturia K. Autism symptoms in anorexia nervosa: a comparative study with females with autism spectrum disorder. Molecular Autism. 2021;12(1):47. https://doi.org/10.1186/s13229-021-00455-5
- Sedgewick F, Kerr-Gaffney J, Leppanen J, Tchanturia K. Anorexia nervosa, autism, and the ADOS: how appropriate is the new algorithm in identifying cases? Frontiers in Psychiatry. 2019;10:507. https://doi.org/10.3389/fpsyt.2019.00507
- Gesi C, Carmassi C, Luciano M, Bossini L, Ricca V, Fagiolini A, et al. Autistic traits in patients with anorexia nervosa, bulimia nervosa or binge eating disorder: a pilot study. European Psychiatry. 2017;41(S1):S100-S. https://doi.org/10.1016/j.eurpsy.2017.01.310
- Nickel K, Maier S, Endres D, Joos A, Maier V, Tebartz van Elst L, et al. Systematic review: overlap between eating, autism spectrum, and attention-deficit/hyperactivity disorder. Frontiers in Psychiatry. 2019;10:708. https://doi.org/10.3389/fpsyt.2019.00708
- Vagni D, Moscone D, Travaglione S, Cotugno A. Using the Ritvo Autism Asperger Diagnostic Scale-Revised (RAADS-R) disentangle the heterogeneity of autistic traits in an Italian eating disorder population. Research in Autism Spectrum Disorders. 2016;32:143-55. https://doi.org/10.1016/j.rasd.2016.10.002
- Sanchez-Cerezo J, Nagularaj L, Gledhill J, Nicholls D. What do we know about the epidemiology of avoidant/restrictive food intake disorder in children and adolescents? A systematic review of the literature. European Eating Disorders Review. 2023;31(2):226-46. https://doi.org/10.1002/erv.2964
- Coglan L, Otasowie J. Avoidant/restrictive food intake disorder: what do we know so far? BJPsych Advances. 2019;25(2):90-8. https://doi.org/10.1192/bja.2018.48
- Calisan Kinter R, Ozbaran B, Inal Kaleli I, Kose S, Bildik T, Ghaziuddin M. The sensory profiles, eating behaviors, and quality of life of children with autism spectrum disorder and avoidant/restrictive food intake disorder. The Psychiatric Quarterly. 2024;95(1):85-106. https://doi.org/10.1007/s11126-023-10063-6
- Papini NM, Bulik CM, Chawner SJRA, Micali N. Prevalence and recurrence of pica behaviors in early childhood within the ALSPAC birth cohort. The International Journal of Eating Disorders. 2024;57(2):400-9. https://doi.org/10.1101/2023.06.04.23290951
- Nielsen S, Anckarsäter H, Gillberg C, Gillberg C, Röstam M, Wentz E. Effects of autism spectrum disorders on outcome in teenage-onset anorexia nervosa evaluated by the Morgan-Russell outcome assessment schedule: a controlled community-based study. Molecular Autism. 2015;6(1):14. https://doi.org/10.1186/s13229-015-0013-4
- Tchanturia K, Smith K, Glennon D, Burhouse A. Towards an improved understanding of the anorexia nervosa and autism spectrum comorbidity: PEACE pathway implementation. Frontiers in Psychiatry. 2020;11:640. https://doi.org/10.3389/fpsyt.2020.00640
- Kinnaird E, Norton C, Tchanturia K. Clinicians' views on working with anorexia nervosa and autism spectrum disorder comorbidity: a qualitative study. BMC Psychiatry. 2017;17(1):292. https://doi.org/10.1186/s12888-017-1455-3
- Speranza M, Loas G, Wallier J, Corcos M. Predictive value of alexithymia in patients with eating disorders: a 3-year prospective study. Journal of Psychosomatic Research. 2007;63(4):365-71. https://doi.org/10.1016/j.jpsychores.2007.03.008
- Kinnaird E, Norton C, Stewart C, Tchanturia K. Same behaviours, different reasons: what do patients with co-occurring anorexia and autism want from treatment? International Review of Psychiatry. 2019;31(4):308-17. https://doi.org/10.1080/09540261.2018.1531831
- Adamson J, Kinnaird E, Glennon D, Oakley M, Tchanturia K. Carers' views on autism and eating disorders comorbidity: qualitative study. BJPsych Open. 2020;6(3):e51. https://doi.org/10.1192/bjo.2020.36
- Tchanturia K, Dandil Y, Li Z, Smith K, Leslie M, Byford S. A novel approach for autism spectrum condition patients with eating disorders: analysis of treatment cost-savings. European Eating Disorders Review. 2021;29(3):514-8. https://doi.org/10.1002/erv.2760
- Li Z, Hutchings-Hay C, Byford S, Tchanturia K. A qualitative evaluation of the pathway for eating disorders and autism developed from clinical experience (PEACE): clinicians' perspective. Frontiers in Psychiatry. 2024;15. https://doi.org/10.3389/fpsyt.2024.1332441
- Brede J, Babb C, Jones C, Elliott M, Zanker C, Tchanturia K, et al. "For me, the anorexia is just a symptom, and the cause is the autism": investigating restrictive eating disorders in autistic women. Journal of Autism and Developmental Disorders. 2020;50(12):4280-96. https://doi.org/10.1007/s10803-020-04479-3
- Babb C, Brede J, Jones CR, Elliott M, Zanker C, Tchanturia K, et al. "It's not that they don't want to access the support... it's the impact of the autism": the experience of eating disorder services from the perspective of autistic women, parents and healthcare professionals. Autism. 2021;25(5):1409-21. https://doi.org/10.1177/1362361321991257
- Murphy S, Flower RL, Jellett R. Women seeking an autism diagnosis in Australia: a qualitative exploration of factors that help and hinder. Autism. 2023;27(3):808-21. https://doi.org/10.1177/13623613221117911
- Lai M-C, Lombardo MV, Auyeung B, Chakrabarti B, Baron-Cohen S. Sex/gender differences and autism: setting the scene for future research. Journal of the American Academy of Child and Adolescent Psychiatry. 2015;54(1):11-24. https://doi.org/10.1016/j.jaac.2014.10.003
- Lewis HK, Foye U. From prevention to peer support: a systematic review exploring the involvement of lived-experience in eating disorder interventions. Mental Health Review Journal. 2022;27(1):1-17. https://doi.org/10.1108/mhrj-04-2021-0033
- Pellicano L, Dinsmore A, Charman T. A future made together: shaping autism research in the UK. Macquarie University (2013).
- Nimbley E, Maloney E, Buchan K, Sader M, Gillespie-Smith K, Duffy F. Barriers and facilitators to ethical co-production with autistic people with an eating disorder. Journal of Eating Disorders. 2024;12(1):113. https://doi.org/10.1002/jclp.23802
- Li Z, Chubinidze D, Croft P, Webb J, Sarpong A, Zesch E, et al. "Don't talk to me like I am an illness": exploring patients' needs using the communication passport in an eating disorder service. Neuropsychiatrie. 2024:1-8. https://doi.org/10.1007/s40211-024-00501-7
- Doherty M, McCowan S, Shaw SC. Autistic SPACE: a novel framework for meeting the needs of autistic people in healthcare settings. British Journal of Hospital Medicine. 2023;84(4):1-9. https://doi.org/10.12968/hmed.2023.0006
- Bradley S, Moore F, Duffy F, Clark L, Suratwala T, Knightsmith P, et al. Camouflaging, not sensory processing or autistic identity, predicts eating disorder symptoms in autistic adults. Autism. 2024:13623613241245749. https://doi.org/10.1177/13623613241245749
- Robertson CE, Baron-Cohen S. Sensory perception in autism. Nature Reviews Neuroscience. 2017;18(11):671-84. https://doi.org/10.1038/nrn.2017.112
- Tint A, Weiss JA, Lunsky Y. Identifying the clinical needs and patterns of health service use of adolescent girls and women with autism spectrum disorder. Autism Research. 2017;10(9):1558-66. https://doi.org/10.1002/aur.1806
- Green VA, Sigafoos J, O'Reilly M, Pituch KA, Didden R, Lancioni GE, et al. Behavioral flexibility in individuals with autism: theory, assessment, and intervention. Autism Research Advances. 2007;63:77. https://doi.org/10.1177/10883576060210040401
- Huke V, Turk J, Saeidi S, Kent A, Morgan JF. The clinical implications of high levels of autism spectrum disorder features in anorexia nervosa: a pilot study. European Eating Disorders Review. 2014;22(2):116-21. https://doi.org/10.1002/erv.2269
- Mandy W, Midouhas E, Hosozawa M, Cable N, Sacker A, Flouri E. Mental health and social difficulties of late-diagnosed autistic children, across childhood and adolescence. Journal of Child Psychology and Psychiatry. 2022;63(11):1405-14. https://doi.org/10.1111/jcpp.13587
- Valenzuela-Zamora AF, Ramírez-Valenzuela DG, Ramos-Jiménez A. Food selectivity and its implications associated with gastrointestinal disorders in children with autism spectrum disorders. Nutrients. 2022;14(13):2660. https://doi.org/10.3390/nu14132660