Early intervention in first-episode psychosis

Author/s
Mark Agius
Citation
Issue 1 Summer 2011
CEPiP.2011.1.35-40
Abstract

There are strong arguments for early intervention in psychosis, including personal, social and economic benefits. The principles of such treatment incorporate the least restrictive approach that is consistent with effective treatment, using the minimum effective dose of antipsychotic medication, retaining social role, involving the family and avoiding relapse.

Keywords: early intervention, psychosis, treatment

Cite as: Cutting Edge Psychiatry in Practice 2011, 1(1):35-40; https://doi.org/10.65031/rnaw2992

References

  1. WHO declaration on Mental Health in Europe 2004.
  2. Agius M, Martic Biocina S, Alptekin K, Rotstein V,Morselli P, Persaud A: Basic Standards for Management of Patients with Serious Mental Illnessin the Community. Psychiatria Danubina 2005;17:42-57.
  3. IRIS Guidelines North Birmingham Mental Health Trust p19; 1999  
  4. Murray R Schizophrenia and Bipolar Disorder; the same but different. In Symposium Long term outcomes in Schizophrenia and Bipolar Disorder.2005.         
  5. Stein L Test M Alternative to mental hospital treatment .1. Conceptual Model, treatment program, and clinical evaluation Archives of General Psychiatry 1980; 37; 392-7. https://doi.org/10.1001/archpsyc.1980.01780170034003
  6. Burns T et al. Intensive versus standard case management for severe psychotic illness; a randomised trial Lancet 1999; 353;2185-9. https://doi.org/10.1016/s0140-6736(98)12191-8
  7. UK700 Group Comparison of intensive and standard case management for patients with psychosis. Rationale of the trial British Journal of Psychiatry 1999; 174;74-8.
  8. Agius M, Zaman R Establishment of anti-psychotic prescribing guidelines and their audit in a new Early Intervention Service in Bedfordshire, UK Advancing Practice in Bedfordshire 2004 1:2 (supp 2004) 23.
  9. Agius M, Zaman R Establishment of Psychopharmacologicalguidelines and Audit of Medication in a new Early Intervention Service in Bedfordshire UK J of Psychopharmacology 2004, suppl, 18,3.           
  10. Dzubur-Kulenovic A, Agius M, Gallagher O, Martic- Biocina S, Zaman R, Jones P Early Intervention in Psychosis. Med Arh 2003; 57(5-6Suppl):61-3.                 
  11. Drury V et al Cognitive therapy and recovery from acute psychosis; a controlled trial I The impact on psychotic symptoms British Journal of Psychiatry 1996 169;593-601. https://doi.org/10.1192/bjp.169.5.593
  12. Kuipers E Fowler D Garety P et al London –East Anglia randomised controlled trial of Cognitive therapy for Psychosis I Effects of the treatment phase. British Journal of Psychiatry 1997;171;319- 27 https://doi.org/10.1192/bjp.171.4.319
  13. Kemp R et al Compliance Therapy in Psychotic Patients; A Randomised Controlled Trial. British Medical Journal:1996; 312;345-9.
  14. Leff J et al A controlled trial of social intervention in families of schizophrenic patients; British Journal of Psychiatry 1982; 141,121-134. https://doi.org/10.1192/bjp.141.2.121
  15. McFarlane W et al. Multiple family groups and psychoeducation in the treatment of schizophrenia Archives of General Psychiatry 1995; 52,679-87. https://doi.org/10.1001/archpsyc.1995.03950200069016
  16. Cullberg J, Levander S, Holmqvist R et al: One year outcome in first episode psychosis patients in the Swedish Parachute Project. Acta Psychiatrica Scandinavica 2002; 106:276-285. https://doi.org/10.1034/j.1600-0447.2002.02376.x
  17. Craig TKJ. Garety P, Power P, RahamanN, Colbert S, Fornells-Ambrojo M et al: The Lambert early onset (LEO) team;randomised controlled trial of the effectiveness of specialised care for early psychosis. BMJ 2004; 329:1067-9. https://doi.org/10.1136/bmj.38246.594873.7c
  18. Garety PA, Craig TK, Dunn M, Fornells-Ambrojo M, et al: Specialised care for early psychosis: symptoms, social functioning and patient satisfaction: randomised controlled trial. British Journal of Psychiatry 2006; 188:37-45. https://doi.org/10.1192/bjp.bp.104.007286
  19. Nordentoft M, Jeeppesen P, Abel M et al: Opus study; suicidal Behaviour, suicidal ideation and hopelessness among patients with first-episode psychosis. One-year follow-up of a randomised controlled trial. British Journal of Psychiatry 2002;181:98-106. https://doi.org/10.1192/bjp.181.43.s98
  20. Nordentoft M et al: OPUS: a randomised multicentre trial of integrated versus standard treatment for patients with a first-episode psychosis secondary publication. Ugeskr Laeger 2006;168:381-384. https://doi.org/10.1016/s0920-9964(08)70087-2
  21. Petersen L et al: A randomised multicentre trial of integrated versus standard treatment for patients with a first episode of psychotic illness. BMJ 2005;331:1065. https://doi.org/10.1136/bmj.331.7524.1065
  22. Petersen L et al: Improving 1-year outcome in first episode psychosis.; OPUS trial. British Journal of Psychiatry 2005; 48(Suppl.):98-103.
  23. Rosenbaum B et al: The Danish National Schizophrenia Project: prospective, comparative longitudinal treatment study of first-episode psychosis. British Journal of Psychiatry 2005;186: 394-399. https://doi.org/10.1192/bjp.186.5.394
  24. Jeppesen P et al: Integrated treatment of firstepisode psychosis; effect of treatment on family burden. British Journal of Psychiatry 2005; 48:85-90.
  25. Agius M, Shah S, Ramkisson R, Murphy S, Zaman R. Three year outcomes of an Early Intervention For Psychosis Service as compared with treatment as usual for first psychotic episodes in a standard Community Mental Health Team-Final Results. Psychiatria Danubina 2007:19;130-138. https://doi.org/10.1016/s0920-9964(06)70462-5