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Cannabis and psychosis

Author/s
Madhavan Seshadri, Mark Agius, Anton Grech, Stanley Zammit
Citation
Issue 1 Summer 2011
CEPiP.2011.1.100-105
Abstract

Several studies have established a link between cannabis and psychosis. However the causal role of cannabis in schizophrenia is still not clear. The aim of this paper is to summarise the literature pertaining to whether cannabis causes psychosis, whether the continued use of cannabis by patients with schizophrenia affects the course of the disease and its treatment, and whether it is possible to reduce cannabis use in patients who have a psychotic disorder.

Keywords: cannabis, psychosis, psychotic illness, schizophrenia

Cite as: Cutting Edge Psychiatry in Practice 2011, 1(1):100-105; https://doi.org/10.65031/fyzs9273

References

  1. Annual report. European monitoring centre for drugs and drug addiction.2010; 44-46.    
  2. Hardwick S, King L. Home Office Cannabis Potency Study. Home Office. 2008; (http://drugs. homeoffice.gov.uk/publication-search/cannabis/potency). https://doi.org/10.3410/f.717968246.793468009
  3. Veling W., Mackenbach J. P., van Os J. & Hoek H. W. Cannabis use and genetic predisposition for schizophrenia: a case-control study. Psychol Med:2008; 38, 1251-6. https://doi.org/10.1017/s0033291708003474
  4. Hall W. & Degenhardt L. (2000). Cannabis use and psychosis: a review of clinical and epidemiological evidence. Aust N Z J Psychiatry 34, 26-34. https://doi.org/10.1046/j.1440-1614.2000.00685.x
  5. Johns A. Psychiatric effects of cannabis. British Journal Psychiatry 2001; 178; 116-122.     
  6. Andreasson S, Allebeck P, Rydberg U. Cannabis and schizophrenia: a longitudinal study of Swedish conscripts. Lancet.1987; 2:1483–6. https://doi.org/10.1016/s0140-6736(87)92620-1
  7. Zammit S, Allebeck P, Andreasson S, Lewis G . Self reported cannabis use as a risk factor for schizophrenia in Swedish Conscripts of 1969: historical cohort study. BMJ. 2002;325:1199 -201. https://doi.org/10.1136/bmj.325.7374.1199
  8. Zammit S, Lewis G. Exploring the relationship between cannabis use and psychosis. Addiction. 2004; 99:1353–5. https://doi.org/10.1111/j.1360-0443.2004.00843.x
  9. Arseneault L, Cannon M, Poulton R, Murray R, Caspi A. & Moffitt T E. Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study. BMJ 325,2002; 1212-3 https://doi.org/10.1136/bmj.325.7374.1212
  10. Van Os J, Bak M, Bijl R V, et al (2002) Cannabis use and psychosis: a longitudinal population-based study. American Journal of Epidemiology, 156, 319 -327. https://doi.org/10.1093/aje/kwf043
  11. Kuepper R, Van Os J, Lieb R, Wittchen H-U, Hofler M, Henquet C. Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study; BMJ 2011;342:d738 https://doi.org/10.1136/bmj.d738
  12. Moore T, Zammit S, Lingford-Hughes A et al;Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review.Lancet. 2007;370: 319 – 328. https://doi.org/10.1016/s0140-6736(07)61162-3
  13. Grech A, Takei N, Murray RM. Comparison of cannabis use in psychotic patients and controls in London and Malta. Schizophrenia Research.1998; 29: 22. https://doi.org/10.1016/s0920-9964(97)88345-4
  14. Zammit S, Moore T, Lingford-Hughes A et al. Effects of cannabis use on outcomes of psychotic disorders: A systematic review: The British Journal of Psychiatry. 2008; 193: 357-363 https://doi.org/10.1192/bjp.bp.107.046375
  15. Foti DJ, Kotov R, Guey LT, Bromet EJ. Cannabis use and the course of schizophrenia: 10-year follow-up after first hospitalization. Am J Psychiatry. 2010 ;167:987-93. https://doi.org/10.1176/appi.ajp.2010.09020189
  16. Maddock C and Babbs M. Interventions for cannabis misuse Adv. Psychiatr. Treat. 2006 12: 432-439 https://doi.org/10.1192/apt.12.6.432
  17. Agius M, Shah S, Ramkisson R, Murphy S, Zaman R. Three year outcomes of an early intervention for psychosis as compared to treatment as usual for first psychotic episodes in a standard community mental health team. Final results. Psychiatria Danubina. 2007, 19:130-8. https://doi.org/10.1016/s0920-9964(06)70462-5
  18. Agius M, Shah S, Ramkisson R, Murphy S, Zaman R. Further development of early intervention in psychosis. Early Intervention in Psychiatry. 2008;2:116-7. https://doi.org/10.1111/j.1751-7893.2008.00068.x
  19. NICE Guidance: Psychosis with coexisting substance misuse. Assessment and management in adults and young people;March 2011