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Bipolar III disorder

Author/s
Holly Cakebread
Citation
Issue 3 Summer 2013
CEPiP.2013;1:184-187
Abstract

Bipolar III is an emerging diagnosis used to describe mania induced by antidepressant therapy prescribed for bipolar patients in a depressive episode. This article reviews the evidence and summarises the safest way to treat bipolar depression.

Keywords: bipolar disorder, antidepressant agents, depressive disorder, manic episode

Cite as: Cutting Edge Psychiatry in Practice 2013, 3(1):184-187; https://doi.org/10.65031/sepc9017

References

  1. Akiskal HS, Pinto O. The evolving bipolar spectrum. Prototypes I, II, III, and IV. Psychiatr Clin North Am. 1999 Sep;22 (3):517-34, vii.     
  2. Akiskal HS, Maser JD, Zeller PJ, Endicott J, Coryell W, Keller M, Warshaw M, Clayton P, Goodwin F. Switching from ‘unipolar’ to bipolar II. An 11-year prospective study of clinical and temperamental predictors in 559 patients. Arch Gen Psychiatry. 1995 Feb;52 (2):114-23. https://doi.org/10.1001/archpsyc.1995.03950140032004
  3. Truman et al, APA 2003                
  4. NICE guidelines CG38 Bipolar – Section 1.4.2 2006. Available from: http://www.nice.org.uk/nicemedia/pdf/CG38niceguideline.pdf.    
  5. Bottlender et al. Mood-stabilisers reduce the risk of developing antidepressant-induced maniform states in acute treatment of bipolar I depressed patients J Affect Disord 2001, 63, 79-83. https://doi.org/10.1016/s0165-0327(00)00172-5
  6. Henry et al. Antidepressant-induced mania in bipolar patients: identification of risk factors. J Clin Psychiat 2001, 62, 249-255. J Clin Psychiatry. 2001 Apr;62 (4):249-55 https://doi.org/10.4088/jcp.v62n0406
  7. Serretti et al, Clinical features of antidepressant associated manic and hypomanic switches in bipolar disorder. Neuropsych. Biol. Psych, 2003; 27: 751-759 https://doi.org/10.1016/s0278-5846(03)00104-0
  8. Mundo et al. Clinical variables related to antidepressant-induced mania in bipolar disorder. J Affect Disord 2006, 92, 227-230. https://doi.org/10.1016/j.jad.2006.01.028
  9. Vacheron-Trystram MN, Braitman A, Cheref S, Auffray L. Antipsychotics in bipolar disorders. Encephale. 2004 Sep-Oct;30 (5):417-24. https://doi.org/10.1016/s0013-7006(04)95456-5
  10. Montgomery SA, Schatzberg AF, Guelfi JD, Kasper S, Nemeroff C, Swann A, Zajecka J Pharmacotherapy of depression and mixed states in bipolar disorder. J Affect Disord. 2000 Sep;59 Suppl 1:S39-S56. https://doi.org/10.1016/s0165-0327(00)00178-6
  11. Hausmann A, Hörtnagl C, Walpoth M, Fuchs M, Conca A [Are there substantial reasons for contraindicating antidepressants in bipolar disorder? Part II: facts or artefacts?]. Neuropsychiatr. 2007;21 (2):131-58       
  12. Salvi V, Fagiolini A, Swartz HA, Maina G, Frank E. The use of antidepressants in bipolar disorder. J Clin Psychiatry. 2008 Aug;69 (8):1307-18. https://doi.org/10.4088/jcp.v69n0816