Bipolar disorder, depression and childhood adversity

Author/s
Jina Pakpoor, Mark Agius
Citation
Issue 3 Summer 2013
CEPiP.2013;1:342-346
Abstract

Childhood adversity is related to an increased risk of developing mental disorders such as major depression, bipolar disorder, schizophrenia and substance abuse, post-traumatic stress disorder, substance abuse, affective problems, anxiety, personality disorders, and suicide. Bipolar disorder and depression are mental disorders that have been particularly associated with childhood abuse. The fact that there is a link between affective illnesses and childhood adversity emphasizes the need for proper assessment for bipolar disorder when these patients present with either depression or mood instability, and that these conditions, when identified, require effective treatment.

Keywords: bipolar disorder, childhood adversity

Cite as: Cutting Edge Psychiatry in Practice 2013, 3(1):342-346; https://doi.org/10.65031/eoxv8413

References

  1. Brietzke E, Sant’anna MK, Jackowski A, Grassi-Oliveira R, Bucker J, Zugman A, Mansur RB, Bressan RA. Impact of childhood stress on psychopathology. Rev Bras Psiquiatr. 2012 Dec;34 (4):480-8. https://doi.org/10.1016/j.rbp.2012.04.009
  2. Chou KL. Childhood sexual abuse and psychiatric disorders in middle-aged and older adults: evidence from the 2007 Adult Psychiatric Morbidity Survey. J Clin Psychiatry. 2012 Nov;73 (11):e1365-71. https://doi.org/10.4088/jcp.12m07946
  3. Cutajar MC, Mullen PE, Ogloff JR, Thomas SD, Wells DL, Spataro J. Psychopathology in a large cohort of sexually abused children followed up to 43 years. Child Abuse Negl. 2010;34 (11):813-22 https://doi.org/10.1016/j.chiabu.2010.04.004
  4. Lee V, Hoaken PN. Cognition, emotion, and neurobiological development: mediating the relation between maltreatment and aggression. Child Maltreat. 2007;12 (3):281-98 https://doi.org/10.1177/1077559507303778
  5. Putnam FW. Ten-year research update review: child sexual abuse. J Am Acad Child Adolesc Psychiatry. 2003;42 (3):269-78. https://doi.org/10.1097/00004583-200303000-00006
  6. Power C, Hertzman C. Social and biological pathways linking early life and adult disease. Br Med Bull 1997;53:210–21.       
  7. Hertzman C, Power C, Matthews S, Manor O. Using an interactive framework of society and lifecourse to explain self-rated health in early adulthood. Soc Sci Med 2001;53:1575–85. https://doi.org/10.1016/s0277-9536(00)00437-8
  8. Ben-Shlomo Y, Kuh D. A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives. Int J Epidemiol 2002;31:285–93. https://doi.org/10.1093/ije/31.2.285
  9. Elstad JI. Childhood adversities and health variations among middle-aged men: a retrospective lifecourse study. Eur J Public Health. 2005 Feb;15 (1):51-8. https://doi.org/10.1093/eurpub/cki114
  10. Weich S, Patterson J, Shaw R, Stewart-Brown S. Family relationships in childhood and common psychiatric disorders in later life: systematic review of prospective studies. Br J Psychiatry. 2009 May;194 (5):392-8. https://doi.org/10.1192/bjp.bp.107.042515
  11. Mueser KT, Goodman LB, Trumbetta SL, Rosenberg SD, Osher C, Vidaver R et al. Trauma and posttraumatic stress disorder in severe mental illness. J Consult Clin Psychol. 1998;66 (3):493-9. https://doi.org/10.1037//0022-006x.66.3.493
  12. Kauer-Sant’anna M, Tramontina JF, Kapczinki F. Transtorno de Estresse Pós-Traumático e Transtorno Bipolar. In: Mari J, Mello MFd, Bressan RA, Andreoli SB, editors. Transtorno de Estresse Pós- Traumático. 1 ed. São Paulo: Manole; 2005. p. 191-5. https://doi.org/10.11606/t.47.2021.tde-08022022-145806
  13. Schafer I, Fisher HL, Aderhold V, Huber B, Hoffmann-Langer L, Golks D et al. Dissociative symptoms in patients with schizophrenia: relationships with childhood trauma and psychotic symptoms. Compr Psychiatry. 2012;53:364-71. https://doi.org/10.1016/j.comppsych.2011.05.010
  14. Alvarez MJ, Roura P, Oses A, Foguet Q, Sola J, Arrufat FX. Prevalence and clinical impact of childhood trauma in patients with severe mental disorders. J Nerv Ment Dis. 2011;199 (3):156-61 https://doi.org/10.1097/nmd.0b013e31820c751c
  15. Nurcombe B. Child sexual abuse I: psychopathology. Aust N Z J Psychiatry. 2000;34 (1):85-91             
  16. Molnar BE, Buka SL, Kessler RC. Child sexual abuse and subsequent psychopathology: results from the National Comorbidity Survey. Am J Public Health. 2001;91 (5):753-60. https://doi.org/10.2105/ajph.91.5.753
  17. Kauer-Sant’Anna M, Tramontina J, Andreazza AC, Cereser K, da Costa S, Santin A et al. Traumatic life events in bipolar disorder: impact on BDNF levels and psychopathology. Bipolar Disord. 2007;9 (Suppl 1):128-35 https://doi.org/10.1111/j.1399-5618.2007.00478.x
  18. Etain B, Henry C, Bellivier F, Mathieu F, Leboyer M. Beyond genetics: childhood affective trauma in bipolar disorder. Bipolar Disord. 2008;10 (8):867-76 https://doi.org/10.1111/j.1399-5618.2008.00635.x
  19. Goldberg JF, Garno JL. Age at onset of bipolar disorder and risk for comorbid borderline personality disorder. Bipolar Disord. 2009;11 (2):205-8. https://doi.org/10.1111/j.1399-5618.2008.00653.x
  20. Neria Y, Bromet EJ, Carlson GA, Naz B. Assaultive trauma and illness course in psychotic bipolar disorder: findings from the Suffolk county mental health project. Acta Psychiatr Scand. 2005;111 (5):380-3. https://doi.org/10.1111/j.1600-0447.2005.00530.x
  21. Hyun M, Friedman SD, Dunner DL. Relationship of childhood physical and sexual abuse to adult bipolar disorder. Bipolar Disord. 2000;2 (2):131-5. https://doi.org/10.1034/j.1399-5618.2000.020206.x
  22. Conus P, Cotton S, Schimmelmann BG, Berk M, Daglas R, McGorry PD et al. Pretreatment and outcome correlates of past sexual and physical trauma in 118 bipolar I disorder patients with a first episode of psychotic mania. Bipolar Disord. 2010;12 (3):244-52. https://doi.org/10.1111/j.1399-5618.2010.00813.x
  23. Levitan RD, Parikh SV, Lesage AD, Hegadoren KM, Adams M, Kennedy SH et al. Major depression in individuals with a history of childhood physical or sexual abuse: relationship to neurovegetative features, mania, and gender. Am J Psychiatry. 1998;155 (12):1746-52. https://doi.org/10.1176/ajp.155.12.1746
  24. Vieira RM, Gauer GJ. Posttraumatic stress disorder and bipolar mood disorder. Rev Bras Psiquiatr. 2003;25 (Suppl 1):55-61.
  25. Leverich GS, Post RM. Course of bipolar illness after history of childhood trauma. Lancet. 2006;367 (9516):1040-2. https://doi.org/10.1016/s0140-6736(06)68450-x
  26. Johnson SL, Miller I. Negative life events and time to recovery from episodes of bipolar disorder. J Abnorm Psychol. 1997;106 (3):449-57.             
  27. Schoedl AF, Costa MC, Mari JJ, Mello MF, Tyrka AR, Carpenter LL et al. The clinical correlates of reported childhood sexual abuse: an association between age at trauma onset and severity of depression and PTSD in adults. J Child Sex Abus. 2010;19 (2):156-70. https://doi.org/10.1080/10538711003615038
  28. Carballedo A, Lisiecka D, Fagan A, Saleh K, Ferguson Y, Connolly G, Meaney J, Frodl T Early life adversity is associated with brain changes in subjects at family risk for depression. World J Biol Psychiatry. 2012 Dec;13 (8):569-78. https://doi.org/10.3109/15622975.2012.661079
  29. Everaerd D, Gerritsen L, Rijpkema M, Frodl T, van Oostrom I, Franke B, Fernández G, Tendolkar I Sex modulates the interactive effect of the serotonin transporter gene polymorphism and childhood adversity on hippocampal volume. Neuropsychopharmacology. 2012 Jul;37 (8):1848-55. https://doi.org/10.1038/npp.2012.32
  30. Carballedo A, Morris D, Zill P, Fahey C, Reinhold E, Meisenzahl E, Bondy B, Gill M, Möller HJ, Frodl T. Brain-derived neurotrophic factor Val66Met polymorphism and early life adversity affect hippocampal volume. Am J Med Genet B Neuropsychiatr Genet. 2013 Mar;162B (2):183-90 https://doi.org/10.1002/ajmg.b.32130
  31. De Bellis MD, Keshavan MS, Clark DB, Casey BJ, Giedd JN, Boring AM et al. A.E. Bennett Research Award. Developmental traumatology. Part II: Brain development. Biol Psychiatry. 1999;45 (10): 1271-84 https://doi.org/10.1016/s0006-3223(99)00045-1
  32. Denenberg VH, Yutzey DA. Hemispheric laterality, behavioral asymmetry, and the effects of early experience in rats. In: Glick SD, editor. Cerebral lateralization in nonhuman species. Orlando: Academic Press; 1985. pp. 109-33. https://doi.org/10.1016/b978-0-12-286480-3.50012-4
  33. Giedd JN, Rumsey JM, Castellanos FX, Rajapakse JC, Kaysen D, Vaituzis AC et al. A quantitative MRI study of the corpus callosum in children and adolescents. Brain Res Dev Brain Res. 1996;91 (2): 274-80. https://doi.org/10.1016/0165-3806(95)00193-x
  34. Keshavan MS, Diwadkar VA, DeBellis M, Dick E, Kotwal R, Rosenberg DR et al. Development of the corpus callosum in childhood, adolescence and early adulthood. Life Sci. 2002;70 (16):1909-22. https://doi.org/10.1016/s0024-3205(02)01492-3
  35. Deoni SC, Mercure E, Blasi A, Gasston D, Thomson A, Johnson M et al. Mapping infant brain myelination with magnetic resonance imaging. J Neurosci. 2011;31 (2):784-91. https://doi.org/10.1523/jneurosci.2106-10.2011
  36. Golier JA, Yehuda R, Lupien SJ, Harvey PD, Grossman R, Elkin A. Memory performance in Holocaust survivors with posttraumatic stress disorder. Am J Psychiatry. 2002;159 (10):1682-8. https://doi.org/10.1176/appi.ajp.159.10.1682
  37. Bremner JD. Does stress damage the brain? Biol Psychiatry. 1999;45 (7):797-805.             
  38. Bremner JD. Long-term effects of childhood abuse on brain and neurobiology. Child Adolesc Psychiatr Clin N Am. 2003;12 (2):271-92. 
  39. Villarreal G, Hamilton DA, Graham DP, Driscoll I, Qualls C, Petropoulos H et al. Reduced area of the corpus callosum in posttraumatic stress disorder. Psychiatry Research: Neuroimaging. 2004;131 (3):227-35 https://doi.org/10.1016/j.pscychresns.2004.05.002